Past Pilot Awards

CCTS funded and co-funded pilot research projects

2022 Funded Pilot Projects

Artificial Intelligence/Machine Learning Pilot Program

Image-Based Phenotyping of Glioblastomas for Clinical Use

Raghu Machiraju, PhD.

College of Engineering

Point of Care Evaluation for Risk of Sudden Cardiac Death

Bryan Whitson, PhD.

College of Medicine

Fair Machine Learning Adaptable to Deployment Environments in Healthcare

Xueru Zhang, PhD.

College of Engineering

Community Engagement and Integrating Special Populations (CE-ISP) Program

Colorectal Cancer Awareness, Research, Education and Screening via the Patient Portal (CARES v2.0)

Aldenise Ewing, PhD.

College of Public Health

FUTURES: Advancing Fertility Care for Male Adolescents and Young Adults with Sickle Cell Disease

Leena Nahata, MD

Nationwide Children's Hospital

Social Determinants of Health Pilot Program

Maternal stress, the microbiome and the maternal exposome

Tamar Gur, MD, PhD

College of Medicine

Transformative Rehabilitation Opportunities for Children with Cerebral Palsy in Appalachian and Rural Communities

Jill Heathercock, PhD.

College of Medicine

Mechanisms by which mate bonding attenuates chemotherapy neurobehavioral side effects

Leah Pyter, PhD.

College of Medicine

A Data-driven Approach to Unravelling the Contextual Social Determinants of Health that Drive Racial/Ethnic Health Disparities 

Macarius Donneyong, PhD., MPH

College of Pharmacy

2021 Funded Pilot Projects

Artificial Intelligence/Machine Learning Pilot Program

Development of an AI-based vertebral fracture risk prediction algorithm for optimizing patient outcomes following stereotactic radiotherapy

Dukagjin Blakaj, MD, PhD.

College of Medicine

Translational development of preference-sensitive predictive analytics

John Bridges, PhD.

College of Medicine

Integrating Multiple Data Sources to Identify Bariatric Surgical Disparities in Franklin County

Keeley Pratt, PhD.

College of Education and Human Ecology

Elucidation of the role of long non-coding RNAs in Congenital Heart Disease

Peter White, PhD.

Nationwide Children's Hospital

Deep Reinforcement Learning for Clinical Decision Support in Sepsis

Ping Zhang, PhD.

College of Medicine

CE-ISP

Sex and GendeR minority cAncer(SANGRIA): Study of healthcare experiences and outcomes

Elizabeth Arthur PhD, APRN-CNP, AOCNP

College of Nursing

Engaging and Integrating the Somali Community in Genomics Research

Bimal Chaudhari, MD

Nationwide Children's Hospital

Identifying Psychosocial Risk Factors Among Spanish-Speaking Families of Children with Craniofacial Conditions: Validation of the Psychosocial Assessment Tool-Craniofacial Version (PAT-CV)

Canice Crerand, PhD.

Nationwide Children's Hospital

NICU views of infant care experiences and symptoms (VOICES): A feasibility study of Spanish-translated study measures

Christine Fortney, PhD., RN

College of Nursing

Co-developing a tailored parent training for adolescents who have accessed residential treatment

Herbell, PhD., RN

College of Nursing

Telemedicine and Telehealth

Feasibility of Pediatric Constraint Induced Movement Therapy Delivered Remotely for Children with Hemiplegic Cerebral Palsy

Warren D. Lo, PhD.

College of Medicine

Skin-Interfaced Biosensors for Personalized, Remote Health Monitoring

Jinghua Li, PhD.

College of Engineering

2020 Funded Pilot Projects

AIML

Deep learning model of histopathologic images to serve as a proxy to predict recurrence risk and chemotherapy benefits in ER-positive/HER2-negative breast cancers

Li, Zaibo MD, PhD., MBA

College of Medicine

Computer-Aided Detection of Advanced Neoplasia in Intraductal Papillary Mucinous Neoplasms Using Confocal Laser Endomicroscopy

Somashekar Krishna MBBS, MPH

College of Medicine

Development of a Deep-Learning Model Prototype to Identify Children Exposed to Parental Incarceration Samantha Boch, PhD.

Nationwide Children's Hospital

DeepCross: a visualized deep learning for signaling pathway crosstalk of prostate cancer disease progression

Lijun Cheng, PhD.

College of Medicine

Deep Transfer Learning of Drug Sensitivity by Integrating Bulk and Single-cell RNA-Seq data

Qin Ma, MD

College of Medicine

Secondary Analysis of Existing Datasets

Improving Outcomes for Infants with Severe Bronchopulmonary Dysplasia through Deep Phenotyping

Matthew Kielt, MD

Nationwide Children's Hospital

Racial disparities in receipt of pain treatment among cancer survivors

Macarius Donneyong, PhD.

College of Pharmacy

2019 Funded Pilot Projects

Secondary Analysis of Existing Datasets

Clarifying the Effects of Media Exposure on ADHD Vulnerability

Theodore Beauchaine, PhD.

College of Arts and Sciences

Exogenous sequences in unmapped transcriptome data from the ORIEN consortium

Daniel Spakowicz, PhD.

College of Medicine

Computational Drug Repurposing for Coronary Artery Diseases (CAD) using MarketScan Data

Ping Zhang, PhD.

College of Medicine

Deriving a Whole-Brain Functional Connectivity Neuromarker in Alzheimer's Disease

Ruchika Prakash, PhD.

College of Arts and Sciences

Systems biology analysis of cancer stem cells in ovarian cancer evolution from tumor initiation to drug resistance

Xiaoli Zhang, PhD.

College of Medicine

Teaming Up on Science for a Healthier Ohio

A novel computational pipeline for functional profiling of human gut microbiome and their associations with human chronic diseases

Qin Ma, PhD.

College of Medicine

Progesterone controls local glucocorticoid regeneration in uterine cervix: Implications for preterm birth

Douglas Kniss, PhD.

College of Medicine

Inflammation in the pathogenesis of discogenic back pain

Devina Walter (Purmessur) Walter, PhD.

College of Engineering

Mobile-App Simulation Platform for Diabetes Self-Management

Kathleen Dungan, MD, MPH

College of Medicine

Decoding social perception in naturalistic contexts

Dylan Wagner, PhD.

College of Arts and Sciences

2018 Funded Pilot Projects

CCTS Opioid Innovation Fund Projects

Evaluating the Effect of a Mind-Body Intervention (SKY Yoga) in Overcoming Opioid Addiction in Adults Undergoing Outpatient Opioid Addiction Treatment
Kathy Wright, PhD, RN, GCNS-BC, PMHCNS-BC 
College of Nursing

Improving Opioid Disposal among Pediatric Patients after Surgery
Jennifer Cooper, MD
Nationwide Children’s Hospital

Building Addiction Knowledge for Frontline Workers: Mobilizing for the Opioid Crisis
Lisa Durham, BSSW
College of Social Work

​​​​​The EMPATH Curriculum Development Project: Cultivating Emergency Physician Behavioral Empathy to Improve Emergency Department Care for Pain and Opioid Abuse
Thomas Terndrup, MD
College of Medicine

Patient Safety Advancement Grants

Hand Hygiene Compliance Monitoring
Team led by Michele Grove, Ann Preble and Justin Smyer

The Effect of Histopathologic Analysis and Tissue Cultures on Inpatient Management of Cellulitis and Pseudocellulitis   
Team led by Benjamin H. Kaffenberger, MD
Team: John Trinidad, MD, MPH and Catherine Chung, MD 

Every Patient out of Bed for Every Meal

Co-PIs: Carmen Quatman, MD & Laura Phieffer, MD
Team: Thuan Ly, MD, Dustin Chase, MD, Catherine Quatman-Yates, DPT, PhD, Tory Hogan, PhD, Sravya Vajapey, MD,  Kari Stammen, AT, CCRP, and Mike Lange, RN, BSN, PCCN

Comprehensive Quality Improvement Strategy to Address Penicillin Allergy Documentation and Evaluation- A Pilot Initiative             

Team led by Kara Wada, MD
Team:  Cory Hussain, MBBS, Lynn Wardlow, PharmD, MBA, BCPS-AQ ID, Erica Reed, PharmD, BCPS-AQ ID and Jennifer Dela-Pena, PharmD, BCPS

 

College of Dentistry Seed Grant

October 2018:

“The role of Harmine in potential of preventing root resorption during orthodontic treatment”
Dr. Toru Deguchi 
Division of Orthodontics

“Effect of crown height on the screw joint stability of screw-retained crowns”
Dr. Lisa Lang
Division of Restorative and Prosthetic Dentistry

April 2018:

"Functions of Discoidin Domain Receptor 1 (DDR1) in Peridontal Health and Disease"
Brian Foster, PhD
Assistant Professor, Division of Biosciences

"Fracture analysis of high density and high-performance polymers used for implant-supported fixed, cantilevered prostheses"
Dr. Burak Yilmaz, DDS, PhD
Associate Professor, Division of Restorative and Prosthetic Dentistry


2017 Funded Pilot Projects

Longitudinal Pilot Awards


Phase 2 Award

Improving Efficacy of Anti-Leishmania Vaccine using a Novel Adjuvant Pentalinonsterol

TEAM PI: Abhay Satoskar, MBBS, MD, PhD, Professor, College of Medicine and College of Arts & Sciences

  • College of Medicine:  Bradford McGwire MD, PhD & Narasimham Parinandi, PhD
  • College of Pharmacy: James Fuchs,  PhD & Doug Kinghorn, PhD
  • College of Veterinary Medicine: Ryan Jennings, DVM, PhD
  • Center for Biostatistics:  Xiaoli Zhang, PhD

 

Phase 3 Award

Disposable Electroceutical Dressings to Treat Chronic Wound Biofilm Infection

TEAM PI:  Sashwati Roy, PhD, Professor, College of Medicine

  • College of Engineering:  Vish Subramaniam, PhD & Shaurya Prakash, PhD
  • College of Medicine:  Gayle Gordillo, MDDan Wozniak, PhD & Hamdy El-Sayed Awad, MD 
  • College of Nursing:   Jodi McDaniel, PhD
  • Departments of Biomedical Informatics and Center for Biostatistics:  Guy Brock, PhD
  • Nationwide Children’s Hospital:  Chris Shilling, MS, Drug & Device Development

A Systems Biology approach to advance the understanding and treatment of Patients with Chronic Granulomatous Diseases using a Novel Ex Vivo Human Model

TEAM PI: Elliott Crouser, MD, Professor, College of Medicine

  • College of Medicine Professors:  Wolfgang Sadee, PhD & Peter White, PhD
  • College of Arts and Sciences: Avner Friedman, PhD

Consultant:  Larry Schlesinger, MD, President & CEO, Texas Biomedical

College of Dentistry Seed Grant

Improve bone marrow aspirate concentrate with a local self-healing injury

Zongyang Sun, DDS, MS, MSD, PhD

FAMEPRO Grant

Resolving Her2 Discrepancies in Breast Cancer Using Genomic Profiling
Rongqin Ren, MD, PhD

Fractional Co2 Laser Therapy for Survivors of Breast and Gynecologic Cancers
Allison M. Quick,  MD

Evaluation of the Psychological Characteristics Impacting Spinal Cord Stimulation Treatment Outcomes
Jose Moreno, PhD

Mismatch repair deficiency in breast cancer: its association with immune checkpoint system and clinical outcome
Zaibo Li, MD, PhD

Molecular Profiling of Cholangiocarcinoma
Wei Chen, MD, PhD

Characterization of Biopsychosocial Factors that Impact Fragility Fracture Outcomes and Secondary Fall Risks
Carmen Quatman MD, PhD

Evaluation of Tools for breast cancer screening decision making in women 75 and older
Heather Hirsch MD

Provider perceptions on the timing of removal of long-acting contraceptive methods
Michelle Isley MD, MPH

Perioperative Use of Gabapentin to Improve Analgesia and Decrease Opioid Use in Rhinoplasty
Leslie Kim MD & Jarrett Heard, MD

HLA Genotypes in patients with staphylococcus infection associated glomerulonephritis
Anjali Satoskar, MD

Posterior Reversible Encephalopathy in patients with hemoglobinopathies post hematopoietic stem cell transplant: A Multi-center retrospective database study
Hemalatha Geetharani Rangarajan, MD

Midwest Strategic Pharma-Academic Research Consortium Awards (SPARC) - Two Year Grants

 

2016-2018

Gene Expression and Microbiome Profiling in Hidradenitis Suppurative to Identify Immunological Bioma
Benjamin Kaffenberger
MD/Assistant Professor, Department of Internal Medicine, Division of Dermatology 

Characterization of micro-RNA (miR) profiles within exosomes from synovial fluid, monocytes, and serum of patients with aggressive rheumatoid arthritis
Wael Jarjour
Associate Professor, Division Director, Rheumatology-Immunology, Internal Medicine

Patient Safety Advancement Grant

Conduction Disturbances After Transcatheter Aortic Valve Replacement: A Strategy of Close Surveillance
Scott Lilly, MD

Reducing the Risk of Narcotic Abuse through Patient and Provider Empowerment
Rajiv Chandawarkar, MD, Amanda Heffner, and Julie Brown

Pulse of the OR: Reducing Operating Room Traffic
Thomas Scharschmidt, MD and Carmen Quatman, MD, PhD

Leveraging electronic medical records, hospital design characteristics, and geospatial modeling for outbreak prediction and prevention of Clostridium difficile infection (CDI) in a hospital setting
Elizabeth Root, MD

Enhanced Recovery After Surgery (ERAS)-Improving Patient Safety with a Digital Platform for Implementation, Adherence and Outcomes
Desmond Dsouza, MD

2016 Funded Pilot Projects

Davis Bremer Award

Clinical translation of a novel bioartificial tissue engineered tracheal graft
Tendy Chiang, MD

Validation of PBX1 as a driver of neuronal differentiation and prognostic biomarker in neuroblastoma
Nilay Shah, MD

Patient Safety Advancement Pilot Awards

Meeting compliance with core measures of The Joint Commission after fragility fracture to improve patient safety outcomes
Steven Ing, MD, MSCE

MyExperience@: A patient-centric safety error reporting mobile technology application
Timothy Huerta, PhD, MS and Melissa Hornor, MD

Feasibility of collecting objective measures during transitional care of depressed adolescents to improve patient safety
Barbara Gracious, MD and Yungui Huang, PhD, MBA

Transforming patient quality and safety measures through mindfulness in motion for healthcare professionals (HCPs): a comparison of cardiac units
Maryanna Klatt, PhD

Midwest Strategic Pharma-Academic Research Consortium Awards (SPARC) - Two Year Grants

2014 - 2016

Microbiome Marker Discovery in Multiple Sclerosis Using Metagenomic Sequencing Technology
OSU  Principal Investigator:  Amy Lovett-Racke, PhD

Molecular analysis of serial kidney biopsies in lupus nephritis to predict early treatment response
OSU  Principal Investigator:  Brad Rovin, MD

2015 Funded Pilot Projects

Longitudinal Pilot Awards

Auto-Scope - Automated Otoscopy to Diagnose Ear Pathology
Metin Gurcan, PhD and Theodoros Teknos, MD


Targeted Immunotherapy of Melanoma with Second Generation ICON
Zhiwei Hu, MD, PhD and William E. Carson, III, MD

Educating Patients on Managing Pet Ownership Risk in Immunocompromised States
Jason Stull, VMD, MPVM, PhD and Thomas Wittum, MS, PhD

Identification of systemic immune activation in the progression of osteoarthritis
Matthew Husa, MD


Determining the role of novel therapeutic target integrin-linked kinase in tumor growth and metastasis of aggressive thyroid cancers
Lawrence Shirley, MD
 

Isofluorine-induced neuroinflammation in children with hydrocephalus
Emmett Whitaker, MD


Strategies to Connect Homeless Youth to a Medical Home Through Community Partnerships
Andrea Bonny, MD

A Community Approach to Lowering the Risk for Type 2 Diabetes in High-Risk Women with a History of GDM
Pamela Salsberry, PhD, RN

2014 Funded Pilot Projects

Longitudinal Pilot Awards

Development of novel STAT3 inhibitor in the treatment of psoriasis
Henry Wong, MD, PhD

Novel bioelectric based dressings for treatment of chronic wound biofilm infections
Sashwati Roy, PhD

Ananoelectroporation patch for non-viral gene and drug delivery in vivo
L James Lee, PhD

Stratification of cancer risk in BRCA mutation carriers
Amanda Toland,PhD, FACMG

Targeting MG53-mediated repair of renal tubular epithelium for treatment of acute kidney injury
Jianjie Ma, PhD

Targeting microRNA to moderate inflammation and CFTR function in cystic fibrosis
Amal Amer, MD, PhD

Immersive 3D gaming therapy for treating hemispatial neglect
Furrukh Khan, PhD

Prescribing adult day health services to reduce emergency department and hospital readmissions
Holly Dabelko-Schoeny, MSW, PhD

A systems biology approach to advance the understanding and treatment of patients with chronic granulomatous diseases using a novel ex vivo human model
Larry Schlesinger, MD

Bench to bedside translation of berry therapy for hemangiomas
Gayle Gordillo, MD, FACS

Discovery of novel vaccine adjuvants from plant-derived sterols
Abhay Satoskar, MD, PhD

Improved diagnosis of mycobacteriumbovis infections in humans and cattle
Shu-Hua Wang, MD, PharmD, MPH, TM

Safety, Feasibility, and Acceptability of Patient-Controlled Sedation for Anxiolysis with Dexmedetomidine (PCS-DEX) for Burn-care Dressing Change
Linda Chlan, PhD, RN, FAAN

Mechanical and compositional analyses of bone tissue
Do-Gyoon Kim, PhD

Contribution of membrane repair to the progression of Dermatomyositis and Polymyositis
Noah Weisleder, PhD

Combinational Effects of Laser Treatment and Pirfenidone on Hypertrophic Burn Scar Reduction
John Kevin Bailey, MD

Predicting patient sensitivity to doxorubicin in advanced soft-tissue sarcoma through a multi-scale similarity algorithm
James Chen, MD

Enhancing oxidative bacterial killing in cystic fibrosis (CF) macrophages
Benjamin Kopp, MD, FAAP

Titration of Inspired Oxygen during Mechanical Ventilation using a Bedside Decision Support Tool
Sonal Pannu, MD

2013 Funded Pilot Projects

Longitudinal Pilot Awards

An Investigation of Novel Biomarkers for Diagnosis of Pulmonary Arterial Hypertension in Patients with Cystic Fibrosis
Don Hayes, MD, MS

Study of Myeloid Derived Suppressor Cells in Patients Receiving Neoadjuvant Chemotherapy for Operable Breast Cancer
Robert Wesolowski, MD

123 Iodine-Labeled HN1-800 Dye Agents for Dual-Modality Intraoperative Surgical Guidance During Resection of Head and Neck Squamos Cell Carcinoma
Chadwick Wright, MD, PhD

2012 Funded Pilot Projects

Longitudinal Pilot Awards

Significance of Bupivacaine in regulation of wound inflammation: mechanisms beyond blocking nerves
Hamdy Elsayed-Awad, MD


Chronic Disease Management in Rural Appalachian Elderly
Deborah Meyer, PhD, RN and Albert Lai, PhD


Integrated Morphological and Genome Analysis for ComputerAided Diagnosis and Computer Intervened Personalized Treatment for Lung Cancer
Lin Yang, PhD and Kun Huang, PhD

Ischemia, glutamate and neuroprotection
Savita Khanna, PhD


Significance of TIMP1 in cerebrovascular collateral circulation during acute ischemic stroke
Cameron Rink, PhD

Development of a transcutaneous immunization patch and assessment of the efficacy afforded against experimental otitis media due to nontypeable Haemophilus influenzae
Lauren O. Bakaletz, PhD; John D. Clements, PhD

Induced pluripotent stem cell modeling of respiratory neuron development
Jose J. Otero, MD, PhD; Jessica Winter, PhD


Development of a Closed, Disposable System for Assembling Tissue Engineered Vascular Grafts (Part 2: Evaluation of the Bioequivalence of Cell Isolation Techniques)
Christopher K. Breuer, MD; Heather Powell, PhD

Prevention of chemotherapy-induced cognitive deficits by docosahexaenoic acid
Maryam B. Lustberg, MD, MPH; A. Courtney DeVries, PhD

Bioavailability and distribution of black raspberry phytochemicals from novel OSU functional foods designed for cancer prevention clinical trials
Lead Candidate Antifungal Drug Development

Yael Vodovotz, PhD

Davis Bremer Pilot Awards

Targeting DNA methylation in Myelodysplastic Syndromes
Katherine Walsh, MD

Human Sternotomy Wound Inflammation and Leukocyte Derived Opioid Peptides
Sujatha P. Bhandary, MD

miR Profiling for Prediction of Post-Hemorrhagic Vasospasm
Ciaran J. Powers

2011 Funded Pilot Projects

Longitudinal Pilot Awards

Assessment of MicroRNA-155 Expression in acute Graft-versus-Host Disease (aGVHD)
Yvonne Efebera, MD


Examining the Effects of Dance Dance Revolution on Mobility, Brain Plasticity and Cognition in Individuals with Multiple Sclerosis
Anne Kloos, PT, PhD, NCS

Evaluation of increased influenza titers during bacterial co-infection
Samantha King, PhD and Renukaradhya Gourapura, DVM, MS, PhD

Repetitive transcranial magnetic stimulation in children with strokes
Warren Lo, MD

Bioinspired Nanofibers for Novel Maxillofacial Prosthetic Adhesives
Bharat Bhushan, PhD and Scott Schricker, PhD

BRF1-Driven Bone augmentation
Sudha Agarwal, PhD

Bone mineralization based diagnosis of oral complications
Do-Gyoon Kim, PhD


Development of a novel advance care planning facilitation tool using the patient health record: A pilot study
Seuli Brill, MD


Applying Artificial Intelligence to ICU Pressure Ulcer Prediction and Prevention
Sookyung Hyun, DNSc, RN


Harnessing time outdoors: environmental correlates of plasma vitamin D
Donald Mutti, OD, PhD

Development of an RNAi therapy for triple negative breast cancer (TNBC)
Robert Lee, PhD and Yasuro Sugimoto, PhD

The role of hsp70,IL-1B and TNF-a responses in recovery after canine spinal cord injury: a pilot investigation
Sarah Moore, DVM, DACVIM

Encapsulated engineered cells for obesity treatment
Ouliana Ziouzenkova, PhD

Community Engagement Pilot Awards

Engaging Rural Appalachia in Clinical Research: A community-based participatory project in Pike County, Ohio
Laureen Smith, PhD, RN

Leveraging Social Networks to Increase Cancer Screening in Appalachia
Mira Katz, PhD

Davis Bremer Pilot Awards

The Effect of Intravitreal Anti-VEGF Agents on the Function of Cutaneous Wound Healing in a Rabbit Model
John Christoforidis, MD

Microvesicles and MicroRNAs as Mediators of Sepsis
Jon Wisler, MD

Effect of glycemic variability on autonomic tone in hospitalized patients with type 2 diabetes
Kathleen Dungan, MD

Local anesthetics infiltration for pain management after cardiac surgery: novel roles beyond blocking nerves
Ravi Tripathi, MD

miR-17~92 Cluster Expression in Bronchopulmonary Dysplasia
Trent Tipple, MD

Additional Awards

Biomarkers of kidney pathology
Brad Rovin, MD

DDR1: a novel player in thrombosis
Gunjan Agarwal, PhD and Richard Gumina, MD

PET imaging agents for tauopathic neurodegenerative diseases
 Jeff Kuret, PhD and Michael Tweedle, PhD  

2010 Funded Pilot Projects

Longitudinal Pilot Awards

Clinical and neurophysiologic identification of sensory dysfunction in children with autism
Alison Lane, PhD, OTR/L 

Pediatric Visual Contrast Sensitivity Test
Angela Brown, PhD

Evaluation of the efficacy of NKT cell-specific adjuvant mediated mucosal influenza vaccine to generate broadly cross-protective candidate vaccine in a pig model
Renukaradhya Gourapura, DVM, MS, PhD, Jordi Torelles, MS, PhD and Chang-Won Lee, DVM, PhD

 

Community Engagement Pilot Awards

Building Environmental Public Health Literacy With An Urban Community: A Pilot Study
Barbara Polivka, MSN, PhD, Mac Crawford, PhD and Rosemary Chaudry, PhD, MHA, MPH

Partnership With Community Properties (CPO) Impact Corporation To Identify Health Concerns Of Female CPO Residents Of Childbearing Age
Thelma Patrick, PhD, RN

Utilization of molecular genotyping and social network analysis to identify outbreaks of community Methicillin-Resistant Staphylococcus aureus (MRSA)
Kurt Stevenson, MD, MPH and Dwight Powell, MD

Comparison of diabetic foot ulcer limb salvage rates in patients receiving specialized wound care versus standard care at OSUMC
Gayle Gordillo, MD

Pilot-testing of a Support Intervention for Shared Decision-making about Depressive Symptoms in Diabetes Mellitus
Celia Wills, PhD, RN

Novel/Innovative Methodologies Pilot Awards

Identification of Altered Transcripts in Motor Neurons and Motor Axons of SMA Mice
Arthur Burghes, PhD

Deciphering the Effects of Cadmium on Airway Epithelial Cells
Estelle Cormet-Boyaka, PhD

Pial Collateral Recruitment and Remodeling in Acute Ischemic Stroke
Cameron Rink, PhD

Role of CD103 in Promoting Tubular Injury During Clinical Renal Allograft Rejection
Gregg Hadley, PhD

Mechanisms in Brain Injury and Protection
Savita Khanna, PhD

Using Laser Capture Microdissection to Query HIV-1 Genomic Diversity in Discrete Regions of Formalin-Fixed Placental Biopsies
Jess Kwiek, Phd

Profiling Circulating Cardiovascular Progenitor Cells
Nicanor Moldovan, PhD

Encapsulated Thermogenic Adipocytes for Obesity Treatment
Ouilana Ziozenkova, PhD

Air Pollution and Perivascular Fat-Mediated Vascular Dysfunction
Qinghua Sun, MD, PhD

AU-Rich Element Containing mRNA Levels in Motor Neurons from Transgenic HSPB1 Mice
Stephen Kolb, MD, Phd

MicroRNA Profiling in Microdissected Pancreatic Precursor Lesions
Thomas Schmittgen, PhD

Modulation of Nitcotinic Receptors by Cytosolic Proteins
Rene Anand, PhD, Stephanie Amici

Cardiovascular Disease, miRNAs, and Aberrant AT1R Expression: Is there a common link?
Terry Elton, PhD

Mathematical and Computational Approaches to Study Burn Propagation and Intervention
Ching-Shan Chou, PhD, Avner Freidman, PhD, Gayle Gordillo, MD, FACS, Heather Powell, PhD and Sabyasachi Biswas, PhD

Quantitative Multiparameter Fluorescent Analysis of Circulating Tumor Cells
Jeffrey Chalmers, PhD and Charles Shapiro, MD

Computer-aided Tools for Identification of Tumor Microenvironment (TME) Biomarkers
Victor Jin, PhD and Michael Ostrowski, PhD

PhenoLIMS - A Laboratory Information System (LMS) for Gleaning Molecular and Morphological Phenotypes in Clinical Outcomes
Raghu Machiraju, PhD and Kun Huang, PhD

Davis Bremer Pilot Awards

Integration of Multimodal Heat Sensitive Microbubbles with Therapeutic Thermal Ablation for Liver Malignancy
Carl Schmidt, MD, MSCI

Gene Therapy of Plastic Surgical Flap Tissues in a Mouse Xenograft Model to Treat Human Colorectal Tumor Implants
Ergun Kocak, MD, MS

Novel Oncolytic Virus Therapy in Squamous Cell Carcinoma
Matthew Old, MD

Cardiovascular Stress Treadmill Imaging in the Young Adult with Tetralogy of Fallot
Stephen Cook, MD, FACC

Other Awards

Discovery, Innovation and New Product Development: Training and Consultative Support Program for CCTS Pilot-Funded Investigators and K-Awardees
Karen Wruck, PhD

Establishment of a multi-investigator team for evaluation of preclinical cardiac stem cell therapy
Mahmood Khan, PhD

Minimally invasive surgery with multimodal imaging guidance
Ronald Xu, PhD

Cerebrovascular collateral recruitment and remodeling in acute ischemic stroke
Cameron Rink, PhD

Lipid mediators play important roles in inflammation regulation, but the lipid mediators that are prevalent in the microenvironment of chronic venous stasis ulcers have not been determined
Jodi McDaniel, PhD

Stem Cell Therapy for Cardiac Regeneration
Konstantinos Boudoulas, MD

AAV5 Mediated Dysferlin Delivery as a Therapeutic Strategy for Dysferlinopathies
Louise Rodino-Klapac, PhD

Bone regeneration: an autologous cell transplantation, tissue engineering and mechanical distraction approach
Zongyang Sun, DDS, PhD

2009 Funded Pilot Projects

Longitudinal Pilot Awards

Live Vaccine Candidates for Human Metapneumovirus
Jianrong Li, DVM, PhD

Ware Washing in Removal of Food-borne Viruses
Melvin Pascall

Novel Rapid Detection of P. Live Vaccine Candidates for Human Metapneumovirus
Jianrong Li, DVM, PhD

PhD Aeruginosa Samples
Jiyoung Lee, PhD

Surgical Delay May Improve Periodontal Surgery Outcomes
Dimitris Tatakis, DDS, PhD

Preventive Topical Gel for Premalignant Oral Lesions
Susan Mallery, DDS, PhD

Effects of Mandibular Devices on Insulin Sensitivity
Ulysses Magalang, MD

Davis Bremer Pilot Awards

Burden of Methicillin Resistant Staphylococcus aureus in the Community – Tackling the Double-Edged Sword
Madhuri Sopirala, MD, PhD


Mechanism of Endothelial Dysfunction in OSA

Rami Khayat, MD

Hospital transmission of Methicillin-Resistant Staphylococcus aureus (MRSA): Characterization of epidemiologic, molecular, geographic, and phylogenetic features
Shu-Hua Wang, MD, MPH & TM


Relationship of red blood cell n-3 and n-6 polyunsaturated fatty acid concentrations to fracture and bone mineral density in the Women’s Health
Steven Ing, MD, MSCE

Additional Awards

Adaptation of Stress Response During Pregnancy
Lisa Christian, PhD


Evaluation of Novel Jak2-STAT3 Inhibitors in Melanoma
Gregory Lesinski, PhD


Musculoskeletal Health and Disorders in Caregivers
Amy R. Darragh, PhD, OTR/L


Detecting Cortical Demyelination with Ultra-Highfield MRI
David Pitt, MD


New Method for Detection of Cancer
Vish Subramaniam, PhD

Laser Capture Microdissection in Equine Laminitis
James Belknap, DVM, PhD

Maternal-Fetal Bonding with Substance Abusing Mothers
Marilyn Lewis, PhD


Improving Islet Cell Transplants Through Gene Transfer

Douglas McCarty, PhD

Recapitulation of Glioma Invasion Using Nanofibers
Sean Lawler, PhD


Training in murine transplant models and transplantation immunology
Christopher A. Adin, DVM, Diplomate


PTHrP and osteoclast biology

Sarandeep Huja, DDS, PhD

Modeling oxygen transport in surgical transfer
Avner Friedman, PhD


Targeting autophagy and AKT signaling with novel small molecules for the treatment of intracellular pathogens
Ching-Shih Chen, PhD


Evaluation of maternal inflammatory markers as predictors of active labor onset among low-risk, nulliparous women: Role of cervical dilation in the diagnosis of true labor
Jeremy Neal, PhD, MS, RNC, Douglas Kniss, PhD and Thelma Patrick, PhD, RN


Genetic Contributions to ADHD Subtypes with Markers of Drug Response in Autism

Julia Pinsonneault, PhD

Molecular Imaging of Inflammation
Sanjay Rajagopalan, MD


Local wound environment in regulation of pain and wound healing in post-sternotomy cardiac surgery patients
Hamdy Elsayed-Awad, MD


Effects of mindfulness training on cognitive and brain plasticity of older adults
Ruchika Shaurya Prakash, PhD


Mechano-Modulation of Hypertrophic Scar Development
Heather Powell, PhD


The Janus face of glutamate in brain injury: from neurotoxin to neuroprotectant
Savita Khanna, PhD


Targeting bone marrow stem cells by oxidized low-density lipoprotein prevents tumor growth and progression
Zhenguo Liu, MD, PhD

Diabetic Hypertriglyceridemia: A novel mechanistic insight that would lead to new drug development and therapies

Sampath Parthasarathy, PhD, MBA, FAHA and Martha Belury, PhD, RD 

Muscle Stem Cells as a New Therapeutic Target in Pancreatic Cancer Cachexia
Denis Guttridge, PhD, Federica Montanaro, PhD, Mark Bloomston, MD and Pete Muscarella, MD 

Viral-Mediated Spinal Glutamate Transporter Over-expression and Visceral Pain
Robert Stephens Jr., PhD and Brian Kaspar, PhD