Multicenter Research Study Support
The Network Capacity Program aims to enhance the quality, efficiency, safety and effectiveness of multi-site clinical research studies through dissemination of adopted best practices and shared resources for Ohio State and Nationwide Children's Hospital investigators. The Network Capacity Program provides an array of multi-site clinical research services and support including the assistance with the development of study organizational and leadership plans, study budgets, SIRB plans, DSMB plans, Manual of Procedures and training of Project Managers of investigator-initiated multi-site clinical research studies.
Ohio State Center for Clinical and Translational Science (CCTS) is committed to strengthening relations within the translational community at Ohio State as well as colleagues at other CTSA institutions and research networks. We are a founding member of three clinical research collaborative networks offering Ohio State investigators access to multiple research sites, shared infrastructure and operational efficiencies to improve the quality, speed and performance of your clinical research study.
For more information, request a service through MyCCTS.
Trial Innovation Network
The Trial Innovation Network (TIN) began in 2016 collaborative initiative amongst Clinical and Translational Science Award (CTSA) institutions in which the primary objective is to enhance multi-site trial operations by leveraging the resources and collective expertise of CTSA members to provide complementary services for all aspects of proposal development and execution. The TIN mission is to address critical roadblocks in clinical research and accelerate the translation of novel interventions into life-saving therapies.
The TIN has a two-fold functionality: it is a pathway connecting Ohio State and Nationwide Children’s Hospital investigators to potential collaborators from other CTSA institutions and resources to strengthen their proposals and to execute proposals better, faster and more cost-effectively. In addition, the TIN facilitates strategic partnerships by assisting investigators from other CTSA institutions to identify collaborators at Ohio State and Nationwide Children’s Hospital based on targeted feasibility assessments.
Access the TIN Overview and Getting Started Handout
The TIN is comprised of three key organizational partners:
Trial Innovation Centers (TICs)
The National Trial Innovation Centers (TICS) focus on operational excellence, operational innovation and quality by design. The TICs responsible for coordinating and providing innovative, high-quality operational support for clinical trials. There are three TICs:
- Duke University / Vanderbilt University
- John Hopkins University / Tufts University
- University of Utah
Recruitment Innovation Centers (RICs)
The National Recruitment Innovation Center (RIC) focused on innovative and evidence-based approaches to participant recruitment, retention and engagement. The RIC is responsible for providing tools and services to enhance participant recruitment and retention.
- Vanderbilt University with partners at Columbia University, University of Utah, Rockefeller University and The Ohio State University
TIN Hub Liaison Team
The Local TIN Hub Liaison Team is the frontline of the TIN leading the Network at the local level by connecting the Hub to the TICs and RIC.
- Ohio State CCTS is a TIN Hub Liaison Team
In addition, the TIN provides Trial Planning and Trial Execution Services.
Trial Planning: Initial Consultations
- Protocol Design
- Study and Budget Feasibility
- Statistical Analysis Plan
- Risk Assessment
- Engagement and Recruitment Plans
- Patient Engagement Studio
- Cohort Discover Leveraging EHR
- Recruitment Training
- Access to unique populations - Rare Diseases
- Key Opinion Leader/Clinical Expertise
Trial Execution Services
- Serve as a Central IRB for your multi-site proposal
- Implement Standard Clinical Trial Agreements for your multi-site proposal
- Provide clinical and data coordinating center services such as regulatory support, project management, data management, development of consent form and case report forms, site selection, initiation and training, performance metrics, Data Safety Monitoring Board (DSMB), study close-out, statistical analysis and publication
- Evaluation and improvement in recruitment plans and tools
Who We Are
The Ohio State University Hub Liaison Team
Medical Director: Henry Wang, MD
TIN Hub Administrator: Amy Bartlett, BA, CCRC
Liaison Team Staff
Recruitment Program Coordinator: Mary Becker
IRB Specialist: Melanie Howell
FDP-CTSA Standard Agreements Specialists: Aimee Nielsen-Link
Regulatory Affairs Specialist: April Green, MACPR, CCRC
Navigating the complicated clinical research landscape can be challenging especially when conducting one’s own investigator-initiated multi-site study. The goal of the TIN is to address the critical roadblocks in clinical trials and accelerate the translation of novel interventions into life-saving therapies. By focusing on operational innovation, operational excellence and collaboration, the TIN supports investigators develop and implement multi-site clinical trials better, faster and more cost-effectively.
- Complimentary services
- Pipeline for finding the collaborators
- Increased competitiveness of applications for NIH
- Access to expertise in multi-center operations (TICs and the RIC) enabling better implementation
If you are interested in submitting a proposal to the TIN, you must contact the Ohio State Hub Liaison Team first for an initial review of your proposal, brief consultation and review by local scientific review committee. Please contact Amy Bartlett, TIN Hub Liaison Team Administrator at 614-247-7732 with questions.