Microfluidic Resistive Pulse Sensing (MRPS) For Characterization of Nanoparticles Seminar

MRPS is rapidly becoming the de facto standard method for measuring nanoparticle size and concentration and is often used as an orthogonal method to flow cytometry for measuring these parameters instead of relying on side or forward scatter in the flow cytometer, which becomes unreliable at lower sizes (typically smaller than 200nm).

This seminar will discuss Spectradyne's nCS1 nanoparticle technology for measurement of particle size distribution and concentration of particles ranging from 50nm to 10µm in size. The nCS1 uses MRPS, an electrical measurement technique. MRPS provides superior resolution to optically based techniques because it measures the actual particle volume directly, with no assumptions necessary as to particle shape or physical characteristics (such as refractive index). As part of the seminar, these optical techniques (such as DLS, NTA and flow cytometry) will be discussed to better understand their limitations.