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Victor Jin, PhD

Award Name OSU CCTS Pilot - Computer, Mathematical, Biostatistical, or Computational Method

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Computer-aided Tools for Indentification of Tumor Microenvironment (TME) Biomarkers

Victor JinVictor Jin, PhD, an assistant professor of Biomedical Informatics is one of four recipients of an OSU CCTS pilot grant under the category of Computer, Mathematical, Biostatistical, or Computational Methods. He is using his grant to study Computer-aided Tools for Identification of Tumor Microenvironment (TME) Biomarkers.

Jin explained his research is focused to “apply machine learning algorithms and statistical methods to decipher the transcriptional regulatory codes in eukaryotic genomes.” His lab is very competitive and right now he has eight students utilizing the lab for at least eighteen different projects, three of which are undergraduates.

His goal is to look at the high throughput data obtained from the collaborators or public sources to address the biological questions. Most of his collaborators are from the cancer center, where they work on many different research topics such as breast cancer, ovarian cancer and prostate cancer.

Jin’s continuing interest for his lab work pertains to his background in the field of biomedical informatics. “Bioinformatics has become an extremely important part of biology research in order to answer a biology question,” he said. “The traditional studies focus on one gene, one promoter in order to know what to study.”

Although he sees the importance in looking at a singular cell or gene on a small scale to see how it works individually, the principle of how a cell works is just a tiny part of the information. “It’s necessary to look at the big picture and find that everything must work together.” Jin said. “When looking at the biology question, the results that you find might not be true for all genes, so you can’t only study one gene.”

The research from Jin’s lab does not rely entirely on wet experiments. More often, they use public data to do their work. Their research tends to be fast paced and very specific in order to compete with other labs. His lab seeks to gather data and develop a new method in order to find interesting conclusions. "It is thanks to the support from the CCTS,” Jin said, “that the lab is able to publish these results.”

Though in the past year a few of his students have graduated and moved on to new positions, he is able to keep up with his research and projects in the lab through the support of his students from the CCTS.

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