Nationwide Children's Viral Vector - GMP Facility
Viral Vector Core generates vectors beginning with a cDNA sequence and ending with the synthesis and purification of gene transfer vectors
The Viral Vector Core is a full-service facility, capable of generating vectors beginning with a cDNA sequence and ending with the synthesis and purification of gene transfer vectors that have passed rigorous quality control assays. The Viral Vector Core supplies recombinant adeno-associated virus (rAAV) and recombinant adenovirus (rAd) vectors of uniform quality to individual research laboratories.
The Core now supports production of six rAAV vector serotypes (rAAV1, rAAV2, rAAV5, rAAV6, rAAV8 and rAAV9), and offers retroviral gene transfer vectors through a collaboration with the Viral Vector Core at Cincinnati Children’s Hospital Medical Center.
Good Manufacturing Practice (GMP) Production Facility
In 2009, the Core established a current Good Manufacturing Practice (cGMP) Production Facility that specializes in the production of recombinant Adeno-Associated viral vectors (rAAV) for use by faculty at Nationwide Children's Hospital, The Ohio State University Medical Center and external academic collaborators.
Contact Viral Vector Core Staff:
K. Reed Clark, PhD, Director